Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or examine is vital for ensuring the purity and protection of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound while in the synthesis of imatinib, a drug that targets distinct forms of cancer, such as chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their research is vital for optimizing the manufacturing system and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to take care of breast cancer, and these intermediates are linked to its output.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the therapy of breast cancer. Various intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers for example ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the treatment of colorectal cancer and small cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, that have various programs, together with antiviral Qualities.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-4 to control blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the 3-d]pyriMidin-7(8H)-one synthesis of varied gluconic acid derivatives, which might be Employed in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A 3-d]pyriMidin-7(8H)-one precursor within the synthesis of canagliflozin, a medication made use of to deal with type two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).