Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity related to bortezomib, a proteasome inhibitor Employed in the therapy of numerous myeloma. Its synthesis or study is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound within the synthesis of imatinib, a drug that targets particular types of cancer, which includes Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their analyze is important for optimizing the production process and making sure higher purity.
Lapatinib CAS NO. 875573-69-6 Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): 2-Deoxy-2 A chemotherapy drug Employed in the therapy of colorectal cancer and smaller mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have a variety of apps, like antiviral Qualities.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of assorted gluconic acid derivatives, that happen to be Utilized in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to control form 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).